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\u809d\u6591\u304c\u3042\u308b\u90e8\u5206\u3067\u306f\u3001\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u5897\u6b96\u56e0\u5b50\uff08VEGF\uff09\u3068\u547c\u3070\u308c\u308b\u7269\u8cea\u304c\u5897\u3048\u3066\u304a\u308a\u3001\u3053\u308c\u304c\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\uff08\u30e1\u30e9\u30cb\u30f3\u3092\u4f5c\u308b\u7d30\u80de\uff09\u306b\u300c\u3082\u3063\u3068\u8272\u3092\u4f5c\u308c\u300d\u3068\u547d\u4ee4\u3092\u51fa\u3057\u7d9a\u3051\u3066\u3057\u307e\u3044\u307e\u3059\u3002 \u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u9ad8\u5468\u6ce2\u306f\u3001\u3053\u308c\u3089\u7570\u5e38\u306a\u8840\u7ba1\u3092\u9069\u5ea6\u306b\u6291\u5236\u3057\u3001\u771f\u76ae\u306e\u708e\u75c7\u3092\u93ae\u3081\u308b\u50cd\u304d\u304c\u3042\u308a\u307e\u3059\u3002 <\/p>\n\n\n\n<p>\u3064\u307e\u308a\u3001<strong><mark style=\"background-color:#fffc00\" class=\"has-inline-color\">\u30e1\u30e9\u30cb\u30f3\u3092\u4f5c\u308b\u300c\u5de5\u5834\u300d\u306b\u5bfe\u3057\u3066\u3001\u9593\u9055\u3063\u305f\u5897\u7523\u547d\u4ee4\u3092\u51fa\u3055\u306a\u3044\u3088\u3046\u306b\u74b0\u5883\u3092\u6574\u3048\u3066\u304f\u308c\u308b<\/mark><\/strong>\u306e\u3067\u3059\u306d\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u30e2\u30fc\u30c9\u306f\u3001\u5f93\u6765\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u3068\u306f\u5168\u304f\u7570\u306a\u308b\u3001\u300c\u539f\u56e0\u304b\u3089\u53d6\u308a\u9664\u304f\u300d\u6839\u672c\u6cbb\u7642\u306e1\u3064\u3067\u3042\u308b\u3068\u3044\u3048\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u6cbb\u7642\u306e\u52b9\u679c\u306f\uff1f<\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1080\" height=\"1080\" src=\"https:\/\/www.soujinkai.or.jp\/himawariBiyouHifu\/wp-content\/uploads\/2026\/03\/\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u6cbb\u7642-1.jpg\" alt=\"\" class=\"wp-image-9245\" srcset=\"https:\/\/www.soujinkai.or.jp\/himawariBiyouHifu\/wp-content\/uploads\/2026\/03\/\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u6cbb\u7642-1.jpg 1080w, https:\/\/www.soujinkai.or.jp\/himawariBiyouHifu\/wp-content\/uploads\/2026\/03\/\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u6cbb\u7642-1-768x768.jpg 768w, https:\/\/www.soujinkai.or.jp\/himawariBiyouHifu\/wp-content\/uploads\/2026\/03\/\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u6cbb\u7642-1-300x300.jpg 300w, https:\/\/www.soujinkai.or.jp\/himawariBiyouHifu\/wp-content\/uploads\/2026\/03\/\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u6cbb\u7642-1-400x400.jpg 400w, https:\/\/www.soujinkai.or.jp\/himawariBiyouHifu\/wp-content\/uploads\/2026\/03\/\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u6cbb\u7642-1-120x120.jpg 120w\" sizes=\"auto, (max-width: 1080px) 100vw, 1080px\" \/><\/figure>\n\n\n\n<p>\u3055\u3066\u3001\u30dd\u30c6\u30f3\u30c4\u30a1\u306b\u3088\u308b\u809d\u6591\u6cbb\u7642\u306f\u7406\u8ad6\u3060\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u52b9\u679c\u3082\u3055\u307e\u3056\u307e\u306a\u8ad6\u6587\u3067\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u30012025\u5e74\u306e\u30a4\u30b9\u30e9\u30a8\u30eb\u3067\u767a\u8868\u3055\u308c\u305f\u8ad6\u6587\u3067\u306f\u3001\u6df7\u5408\u578b\u809d\u6591\uff08\u808c\u306e\u8868\u9762\u3068\u6df1\u3044\u5c64\u306e\u4e21\u65b9\u306b\u30b7\u30df\u304c\u3042\u308b\u30bf\u30a4\u30d7\uff09\u306e\u5973\u602714\u540d\uff0835\u301c48\u6b73\uff09\u3092\u5bfe\u8c61\u306b\u3001\u305d\u306e\u52b9\u679c\u3092\u8abf\u3079\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>\u9ad8\u5468\u6ce2\u30de\u30a4\u30af\u30ed\u30cb\u30fc\u30c9\u30eb\u3067\u808c\u3092\u51e6\u7f6e\u3002<\/li>\n\n\n\n<li>\u305d\u306e\u76f4\u5f8c\u306b\u30014%\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u6db2\u3092\u5857\u5e03\u3057\u3066\u6d78\u900f\u3055\u305b\u308b\u3002<\/li>\n<\/ol>\n\n\n\n<p>\u3068\u3044\u3046\u65b9\u6cd5\u3067\u30013\u9031\u9593\u304a\u304d\u306b\u5408\u8a084\u56de\u306e\u6cbb\u7642\u3092\u884c\u3044\u3001\u6700\u7d42\u6cbb\u7642\u304b\u30893\u304b\u6708\u5f8c\u306b\u5199\u771f\u3068\u91cd\u75c7\u5ea6\u30b9\u30b3\u30a2\uff08mMASI\uff09\u3067\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3059\u308b\u3068\u300114\u540d\u4e2d13\u540d\uff0893%\uff09\u3067\u809d\u6591\u304c\u8584\u304f\u306a\u308a\u3001\u91cd\u75c7\u5ea6\u30b9\u30b3\u30a2\u3082\u5e73\u5747\u3067 <strong>5.22 \u2192 3.6<\/strong> \u3078\u3068\u6539\u5584\uff08<strong>\u5168\u4f53\u3067\u7d0431%\u306e\u6539\u5584<\/strong>\uff09\u3057\u3066\u3044\u305f\u306e\u3067\u3059\u3002\uff08\u4e0a\u8a18\u5199\u771f\u53c2\u7167\uff09<\/p>\n\n\n\n<p>\u809d\u6591\u6cbb\u7642\u306f\u975e\u5e38\u306b\u96e3\u3057\u304f\u6cbb\u7642\u52b9\u679c\u304c\u306a\u304b\u306a\u304b\u51fa\u306b\u304f\u3044\u4e2d\u3067\u3001\u304b\u306a\u308a\u306e\u52b9\u679c\u3092\u3042\u3052\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u30012022\u5e74\u306e\u30bf\u30a4\u304b\u3089\u306e\u8ad6\u6587\u3067\u306f30\u540d\u306e\u5973\u6027\uff08\u5e73\u5747\u5e74\u9f6243\u6b73\uff09\u306b\u5bfe\u3057\u3066\u3001\u809d\u6591\u6cbb\u7642\u306b\u30de\u30a4\u30af\u30ed\u30cb\u30fc\u30c9\u30eb\u306e\u307f\u3092\u4f7f\u7528\u3057\u305f\u8a66\u9a13\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u672c\u8a66\u9a13\u3067\u306f\u30012\u9031\u9593\u304a\u304d\u306b\u5408\u8a08 <strong>3\u56de<\/strong> \u306e\u65bd\u8853\u3092\u884c\u3044\u3001\u305d\u306e\u5f8c6\u30f6\u6708\u9593\u7d4c\u904e\u3092\u89b3\u5bdf\u3057\u3066\u3044\u307e\u3059\u3002\u3059\u308b\u3068\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u6539\u5584\u304c\u307f\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u809d\u6591\u306e\u91cd\u75c7\u5ea6\uff08mMESI\u30b9\u30b3\u30a2\uff09<\/strong>\uff1a\u6700\u7d42\u6cbb\u7642\u304b\u3089\u308f\u305a\u304b2\u9031\u9593\u5f8c\u306b\u306f\u6539\u5584\uff08$-1.206$\uff09\u304c\u59cb\u307e\u308a\u30016\u30f6\u6708\u5f8c\u307e\u3067\u7d99\u7d9a\u3057\u307e\u3057\u305f\uff08\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u304b\u3089\u5e73\u5747\u3067 <strong>1.287$ \u30dd\u30a4\u30f3\u30c8\u6e1b\u5c11<\/strong>\uff09<\/li>\n\n\n\n<li><strong>\u30e1\u30e9\u30cb\u30f3\u6307\u6570\uff08MI\uff09<\/strong>\uff1a\u6cbb\u76421\u30f6\u6708\u5f8c\uff08-24\u30dd\u30a4\u30f3\u30c8\uff09\u304b\u3089\u6709\u610f\u306a\u6539\u5584\u304c\u3042\u308a\u307e\u3057\u305f\u30026\u30ab\u6708\u5f8c\u3082\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u304b\u3089\u5e73\u574763\u30dd\u30a4\u30f3\u30c8\u3068\u6e1b\u5c11\u3057\u305f\u3068\u306e\u3053\u3068\u3067\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u808c\u306e\u30ad\u30e1\u3084\u7c97\u3055\u306e\u6307\u6570\u3082\u6cbb\u76422\u9031\u9593\u5f8c\u304b\u30890.84\u30dd\u30a4\u30f3\u30c8\u30016\u304b\u6708\u5f8c\u306e\u5e73\u5747\u3067\u30821.136\u30dd\u30a4\u30f3\u30c8\u6e1b\u3063\u3066\u3044\u305f\u3068\u3044\u3046\u306e\u3067\u3059\u304b\u3089\u3001\u9a5a\u304d\u3067\u3059\u3088\u306d\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u808c\u306e\u708e\u75c7\u3084\u8d64\u8eab\u3082\u6cbb\u7642<strong>2\u30f6\u6708\u5f8c<\/strong>\u306b\u6e1b\u5c11\uff08-26\u30dd\u30a4\u30f3\u30c8\uff09\u304c\u898b\u3089\u308c\u305f\u3068\u306e\u3053\u3068\u3067\u3059<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u30c8\u30e9\u30f3\u30b5\u30df\u30f3\u3068\u7d44\u307f\u5408\u308f\u305b\u308b\u8a66\u9a13\u304c\u591a\u3044\u3067\u3059\u304c\u3001\u30de\u30a4\u30af\u30ed\u30cb\u30fc\u30c9\u30eb\u306e\u307f\u3067\u3082\u5341\u5206\u52b9\u679c\u304c\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3059\u306d\u3002<\/p>\n\n\n\n<p>\uff08\u53c2\u7167\uff1a<a href=\"https:\/\/link.springer.com\/article\/10.1007\/s13555-022-00728-8\" title=\"\">Efficacy and Safety of Using Noninsulated Microneedle Radiofrequency Alone Versus in Combination with Polynucleotides for the Treatment of Melasma: A Pilot Study<\/a>\uff09<br>\uff08\u53c2\u7167\uff1a<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40586253\/\" title=\"\">Topical Tranexamic Acid-mediated with Non-insulated Microneedling Radiofrequency for the Treatment of Melasma<\/a>\uff09<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u6cbb\u7642\u306f\u4f55\u56de\u304f\u3089\u3044\u3084\u3063\u305f\u65b9\u304c\u3088\u3044\uff1f<\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1080\" height=\"1080\" src=\"https:\/\/www.soujinkai.or.jp\/himawariBiyouHifu\/wp-content\/uploads\/2026\/03\/\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u6cbb\u7642-2.webp\" alt=\"\" class=\"wp-image-9247\" srcset=\"https:\/\/www.soujinkai.or.jp\/himawariBiyouHifu\/wp-content\/uploads\/2026\/03\/\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u6cbb\u7642-2.webp 1080w, https:\/\/www.soujinkai.or.jp\/himawariBiyouHifu\/wp-content\/uploads\/2026\/03\/\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u6cbb\u7642-2-768x768.webp 768w, https:\/\/www.soujinkai.or.jp\/himawariBiyouHifu\/wp-content\/uploads\/2026\/03\/\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u6cbb\u7642-2-300x300.webp 300w, https:\/\/www.soujinkai.or.jp\/himawariBiyouHifu\/wp-content\/uploads\/2026\/03\/\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u6cbb\u7642-2-400x400.webp 400w, https:\/\/www.soujinkai.or.jp\/himawariBiyouHifu\/wp-content\/uploads\/2026\/03\/\u30dd\u30c6\u30f3\u30c4\u30a1\u306e\u809d\u6591\u6cbb\u7642-2-120x120.webp 120w\" sizes=\"auto, (max-width: 1080px) 100vw, 1080px\" 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